No [man] whose testes are crushed or whose member is cut off shall be admitted into the congregation of GOD.

Rav Yehuda said that Shmuel said: A man wounded with crushed testicles at the hand of Heaven.

Whenever we have used the term "unacceptable" in this context, the implication is that [the malady] was not caused by the hand of heaven, e.g., [his testicles] were severed by a man or a dog, he was struck by a sharp end, or the like. If, however, he was born with maimed testicles or a severed member, or without testicles, he became ill because of a bodily ailment and these organs ceased to function, or an ulcer arose in them that caused them to waste away or be severed, he is permitted to marry among the Jewish people. For all of these blemishes are caused by the hand of heaven.

The disqualifications they have said about this, is when it was not an act of God, such as [his testicles] were severed by a man or a dog, he was struck by a thorn, or things similar to that. However, if he was born with a severed urethra, or crushed testicles, or was born without testicles, or he became ill because of a sickness of the body and these organs were terminated, or a blister occurred which made them wither or be severed, he is kosher to enter [marry] into the Jewish people. For all of these were acts of God, according to the Rambam. But Rashi and the Rosh only call it an act of God if it was lightning, or hail, or within the womb, but not through sickness, which is considered an act of man, and it disqualifies, and the Rosh writes that the Jerusalem Talmud implies this.

(24) You shall not offer to GOD anything [with its testes] bruised or crushed or torn or cut. You shall have no such practices in your own land, (25) nor shall you accept such [animals] from a foreigner for offering as food for your God, for they are mutilated, they have a defect; they shall not be accepted in your favor.

Yehuda and Ḥizkiyya, were twins, but one of them was fully developed after nine months of pregnancy and one was fully developed at the beginning of the seventh month, and they were born two months apart. Yehudit, the wife of Rabbi Ḥiyya, had acute birthing pain from these unusual deliveries. She changed her clothes to prevent Rabbi Ḥiyya from recognizing her and came before Rabbi Ḥiyya to ask him a halakhic question. She said: Is a woman commanded to be fruitful and multiply? He said to her: No. She went and drank an infertility potion. Eventually the matter was revealed, and Rabbi Ḥiyya found out about what Yehudit had done. He said to her: If only you had given birth to one more belly for me, i.e., another set of twins. As the Master said: Yehuda and Ḥizkiyya were twin brothers and became prominent Torah scholars, and Pazi and Tavi, Rabbi Ḥiyya’s daughters, were twin sisters, and became the matriarchs of families of distinguished Torah scholars.

The Gemara discussed the remedy for jaundice, saying that one should drink two of the ingredients mentioned together with beer, and one becomes sterile from it. The Gemara asks: And is it permitted to cause sterility? Wasn’t it taught in a baraita: From where is it derived that castration of a man is prohibited? The verse states: “Those whose testicles are bruised, or crushed, or torn, or cut, shall not be offered to the Lord, and you shall not do this in your land” (Leviticus 22:24), meaning that you shall not do it to yourselves; this is the statement of Rabbi Ḥanina. Apparently, it is prohibited to castrate a man. The Gemara answers: This prohibition applies only in a case where one intends to castrate. Here, in the cure for jaundice, the sterility happens on its own, incidental to the treatment. Proof is cited from that which Rabbi Yoḥanan said: One who seeks to castrate a rooster should remove its comb and it will become castrated on its own. Incidental castration is permitted. The Gemara rejects the proof. Didn’t Rav Ashi say: It is arrogance that it assumes when it has its comb, and when the comb is removed it becomes depressed and no longer procreates. However, it is not actually castrated... Rather, we must say that it is permitted to use a remedy that causes sterility in an old man who is no longer capable of procreating. The Gemara asks: Didn’t Rabbi Yoḥanan say with regard to remedies that restore procreative ability: These have restored me to my youth? Apparently, even an elderly man can procreate with the proper remedy. Rather, the remedy for jaundice was discussed with regard to a woman, who is not commanded to reproduce. The Gemara asks: And according to Rabbi Yoḥanan ben Beroka, who said: The mitzva is incumbent on both of them, the man and the woman, as it states: “And God blessed them and God said to them: Be fruitful and multiply and fill the earth and conquer it” (Genesis 1:28), what is there to say? How could a woman use this remedy? In his opinion a woman is also commanded to procreate. The Gemara answers: In his opinion, this remedy may be used for an elderly woman or, alternatively, for a barren woman. He would agree that there is no prohibition to cause infertility in a woman who cannot conceive.

A person who gives a cup of root drink to a person or any living thing in order to render him impotent, this is forbidden. But, he (the giver of the drink) is not lashed. However, for a woman it is permitted to drink this root drink in order that she become impotent so she cannot give birth.

If a man married a woman and stayed with her for ten years and she did not give birth, he is no longer permitted to neglect the mitzva to be fruitful and multiply. Consequently, he must either divorce her and marry someone else, or take another wife while still married to her.

Although there is no explicit proof for the matter that one must take another wife if he has not had children after ten years of marriage, there is an allusion to the matter, as the verse states: “And Sarai, Abram’s wife, took Hagar…after Abram had dwelled ten years in the land of Canaan, and gave her to Abram her husband to be his wife” (Genesis 16:3).

If a man married a woman and stayed with her for ten years and did not produce children, he must divorce her and give her Ketubah, or marry another woman who can bear children. If he is unwilling, we force him to divorce. If he said, "I will not have intercourse with her. I will live with her with witnesses so that I will not be secluded with her." Whether she said this, or he said it, we do not listen; instead we require him to divorce or marry a child bearing woman. Rem"a: Some authorities say that this is true if they had no children at all. If, however, she birthed a viable child, even though he has not yet fulfilled obligation to be fruitful, we do not force him to divorce her. See (Shulchan Arukh, Even HaEzer 1), that these days we never force a divorce. A man is believed to say that he knows himself to be sterile, and we do not force him to marry a woman.